Love it
"I've been using Phyto Nature E² for a few weeks and really enjoy the texture and how my skin feels after. It absorbs quickly, layers well under moisturizer, and my skin looks smoother and more refreshed overall."
renew + resurface
Couldn't load pickup availability
recommended for:
Daily exosome leave-on visibly smooths and supports skin regeneration. Formulated with next-gen exosomes and enzymes, this lightweight, silky leave-on helps reawaken skin’s natural surface renewal process, improving natural regeneration by 86%.*
Exfoliating enzymes help clear away dull surface cells, revealing smoother, brighter skin. A regenerative exosome blend acts in multiple layers of skin’s surface, visibly diminishing fine lines and wrinkles. In an independent clinical study, fine lines and wrinkles were visibly diminished in 2 weeks.*
*Versus untreated skin. Based on in vitro testing.
**Results at 2 weeks, based on a reduction in visible signs of skin aging in an independent clinical study with 32 subjects, 2 applications/day.
recommended for:
Daily exosome leave-on visibly smooths and supports skin regeneration. Formulated with next-gen exosomes and enzymes, this lightweight, silky leave-on helps reawaken skin’s natural surface renewal process, improving natural regeneration by 86%.*
Exfoliating enzymes help clear away dull surface cells, revealing smoother, brighter skin. A regenerative exosome blend acts in multiple layers of skin’s surface, visibly diminishing fine lines and wrinkles. In an independent clinical study, fine lines and wrinkles were visibly diminished in 2 weeks.*
*Versus untreated skin. Based on in vitro testing.
**Results at 2 weeks, based on a reduction in visible signs of skin aging in an independent clinical study with 32 subjects, 2 applications/day.
Apply to clean skin. Allow to absorb, then follow with the rest of your skin care routine. Use twice daily.
Pumpkin enzyme: Exfoliates to reveal brighter, smoother skin daily
Regenerative exosome blend: Acts in multiple layers of skin’s surface, visibly diminishing fine lines and wrinkles
Botanical blend with phyto glycogen + prickly pear: Visibly brightens and smooths
Bio-fermented acetyl glucosamine: Hydrates and provides antioxidant protection
Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral.
Dermalogica is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are complete, up-to-date and/or error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.


60 minutes
firm + retexturizing treatment

booster
clinically proven to enhance post procedure results
Overall rating: 4.8013935 / 5 from 574 reviews.
Phyto Nature e² is a leave-on product recommended for mature or prematurely-aging skin, known for visibly smoothing and supporting skin regeneration. It is formulated with next-gen exosomes and enzymes, offering lightweight and silky texture that absorbs quickly without residue. Many customers report smoother, firmer, and more radiant skin, with noticeable results in fine lines and wrinkles within two weeks.
Review topics: [absorbs, redness, improvement, difference, feels, skin, looks, buy, reduction, texture, results, treatment, smell, glow, wrinkles, exfoliant, formula, face, irritation, lines, bottle, complexion, packaging, serum, ingredients, residue, consistency, works, appearance, fragrance].
"I've been using Phyto Nature E² for a few weeks and really enjoy the texture and how my skin feels after. It absorbs quickly, layers well under moisturizer, and my skin looks smoother and more refreshed overall."
"I've been using Phyto Nature E² Regenerating Daily and I'm really impressed with the results. My skin looks smoother, healthier, and noticeably more youthful. It feels hydrated without being greasy, and my complexion has a nice glow. After using it consistently, I've noticed my skin looks firmer and more refreshed. It's become one of my favorite skincare products, and I would definitely recommend it to anyone looking to improve the overall appearance of their skin."
"This is the best product to date. It is the first thing i put on after I cleanse my face. It blends in to the perfect combination of hydration and glow. After applying this i apply the serum of choice. This product is a game changer."
"I absolutely love this product. I’m 70 years old and have been using it for a month. My skin looks smoother. My pores are tighter. It is definitely making a positive difference."
"I’ve only been using the products for two weeks so I can’t really say that it’s a good thing. I’ve had to cut back to once a day as I have experienced stinging. That being said I have loved all Dermalogica for a long time and I have high hopes. At 74 years old my skin looks great and I give most of the credit to Dermalogica,"
"It’s so lightweight you can layer a serum over top I like to use the morning viramim c serum with it"
"As a 69 year old, and very concerned of looking fresh and hopefully a looking a little youthful for my age, ‘regenerating’ is essential for the price. Love the feel, the smell and the benefits!"
"I wanted to love this product, but for the price it just doesn't seem to be doing what I had hoped it would. I'm not a fan of the consistency of the material when I put it on my face. It almost feels like a mask-but not in a good way."
"Love, love, love Phyto Nature!!! My skin looks incredible and people have asked me if I have had botox, which I never have."
"Gives your skin a reset after just a few uses. . you have to put it on first to get the most out of it. . put on bare skin let it doak it then the rest"