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"Can’t live without smart response serum use it every day"
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skincare just got smarter. soothes. firms. brightens. hydrates.
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Apply each morning and night after cleansing and toning. Allow one minute for product absorption.
Water/Aqua/Eau, Glycerin, Coco-Caprylate/Caprate, PPG-24-Glycereth-24, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Sodium Acrylates Crosspolymer-2, C18-36 Acid Triglyceride, Sodium Polyacryloyldimethyl Taurate, Hydroxyacetophenone, Jojoba Esters, Olive Oil Decyl Esters, Phytosterols, Cornus Officinalis Fruit Extract, Hydrolyzed Wheat Flour, Sodium Mannose Phosphate, Phytosteryl Macadamiate, Hydrolyzed Beta-Glucan, Mimosa Tenuiflora Bark Extract, Ilex Paraguariensis Leaf Extract, Sea Salt, Ferula Galbaniflua (Galbanum) Resin Oil, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Extract, Citrus Aurantium Dulcis (Orange) Peel Oil, Juniperus Virginiana Oil, Pelargonium Graveolens Flower Oil, Vetiveria Zizanoides Root Oil, Prunus Amygdalus Amara (Bitter Almond) Kernel Oil, Chlorella Vulgaris Extract, Dipteryx Odorata Seed Extract, Lactic Acid, Bentonite, C12-18 Acid Triglyceride, Squalene, Tocopherol, Sodium Acetylated Hyaluronate, Mannose, Citric Acid, Hydrated Silica, Sodium Benzoate, Potassium Sorbate, Citronellol, Geraniol, Coumarin, Linalool, Limonene.
Dermalogica is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are complete, up-to-date and/or error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.

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Overall rating: 4.746507 / 5 from 1002 reviews.
Customers praise the Smart Response Serum for its smooth, silky texture and pleasant smell. They appreciate its ability to hydrate and plump skin, making it look fresh and healthy. The serum is also noted for its effectiveness in reducing fine lines and brightening skin, with many customers reporting noticeable improvements.
Review topics: [size, absorbs, results, issues, ingredients, irritation, improvement, price, wrinkles, weight, smell, works, quality, fragrance, spots, use, benefits, feels, texture, lines, packaging, design, formula, difference, skin, looks, amount, effect, glow, face].
"Can’t live without smart response serum use it every day"
"I’ve used Dermalogica for years, and Smart Response Serum is a standout. It leaves my skin feeling renewed, smooth, and deeply hydrated. I’ve even received compliments while wearing only this serum. It’s become an essential in my routine."
"Have used for 3 days and I love it! Redness has improved and I have sensitive skin but so far so good!!. It’s pricey but I think will last a long time."
"Love this serum and carrying it around when my skin needs a boost of hydration"
"The bottle design is nice and packaging. Quick delivery! I feel hydrated all day but I'm not sure if it brightens or I feel more glowy for the price. I do love all dermalogica products though."
"Firstly I received the sample, and then fell in love with this product!I use it before going to bed, and my skin says thanks to me, it's so glowing and soft!"
"I wanted to finish using the product so that I can write an honest review. This is the first serum I’ve bought from Dermalogica. I bought it mainly to target my dark spots. Tbh it has not brightened my dark spots and I used the whole bottle. I do have to say, base on a recent picture, my pores have tightened and the texture has changed. I’m trying other serums from Dermalogica and I will review those accordingly. Also, for the price I paid, the serum finished within a month. I’ve used other products whereby my serum lasted at least 3 to 4 months and longer if I wanted to stretch it and it’s within the same price range. I was very dissatisfied with that. Because I wanted it mainly to brighten and did not expect it finish this quickly, I’m giving it this rating. I’ve bought other products from the brand and I will review accordingly, too."
"Perfect serum for the cold weather. It is thick and goes on so smoothly. Definitely helps with hydration and works wonderful when applying moisterizer on top of it."
"This is my favorite product by Dermalogica. I feel like it smooths my face like no other produce. I like putting it on over my foundation for a little trick."
"The Smart Response Serum delivered results I could actually see. My skin looked noticeably smoother, brighter, and more even in tone, and the difference between my before-and-after photos was undeniable. The formula absorbs beautifully—lightweight, hydrating, and never sticky—and it leaves my complexion calm, radiant, and refreshed. This has quickly become a standout step in my routine."